Dr. Lyles is a graduate of the University of Michigan Six Year Premedical Medical Program. He completed his psychiatric residency and APA/NIMH Minority Fellowship at Duke University Medical Center where he was the recipient of the North Carolina Neuropsychiatric Association Resident of the Year Award. He was an Assistant Professor of Psychiatry and Associate Director of Outpatient Services at The University of Kentucky College of Medicine.

He moved to Atlanta in 1986 to enter private practice and has served as the medical director of a partial hospitalization program, outpatient chemical dependency program and inpatient psychiatric units at three different facilities. He has worked in the private sector in a community mental health center, state psychiatric hospital and county, state and federal prisons. He is committed to raising the standard of care in the community by teaching gatekeepers such as clergy and primary care doctors, along with lay groups.

He is a consultant to a variety of community organizations ranging from religious organizations to internet sites to professional athletics such as The Atlanta Hawks. He is board certified in Adult Psychiatry by The American Board of Psychiatry and Neurology. His major areas of clinical activity are mood disorders, anxiety disorders and ADHD.

He has published over 60 publications and videos and serves on the speaking and advisory boards for several pharmaceutical companies.